A mosaic Turner syndrome diagnosis can raise more questions than answers, especially when your dream is to become a parent.

The truth is, getting pregnant with mosaic Turner syndrome is sometimes possible, but it’s not always straightforward. Fortunately, you’re not alone and you do have options.

In this guide, we’ll break down what to know about mosaic syndrome and pregnancy, explore your fertility options and share how surrogacy can support your journey toward parenthood.

Not sure where to start? Our surrogacy specialists can walk you through your options if getting pregnant with Turner Mosaic Syndrome has been unsuccessful. Talk to us today.  

Is Getting Pregnant With Mosaic Turner Syndrome Possible?

The short answer is: it’s possible, but rare.

Women with mosaic Turner syndrome have a mix of normal (46,XX) and altered (45,X) chromosomes. This mosaicism can result in partially preserved ovarian function, which is essential for natural conception.

While most women with Turner syndrome experience premature ovarian failure, those with mosaicism may retain some viable eggs, particularly during adolescence or early adulthood.

That said, getting pregnant with mosaic Turner syndrome remains uncommon without medical intervention.

Early fertility evaluation is essential if you’re considering this route. If you have menstrual cycles and signs of ovarian function, your reproductive endocrinologist may explore natural or minimally assisted conception.

The Link Between Mosaic Turner Syndrome and Miscarriages

One of the most emotionally difficult aspects of mosaic syndrome and pregnancy is the increased risk of miscarriage. In one study of 130 women with the diagnosis, only 1 in 7 were able to get pregnant naturally and approximately 30% of those pregnancies ended in miscarriage.

Another study documented a woman with nine spontaneous pregnancies. Six of those ended in first-trimester miscarriage, stillbirth or infant death.

Women with Turner mosaicism who conceive, either naturally or through IVF, face a significantly higher chance of:

• First-trimester miscarriage
• Recurrent pregnancy loss
• Stillbirth due to fetal chromosomal abnormalities

This is largely due to the compromised egg quality and chromosomal irregularities that mosaicism can introduce.

Can You Do IVF With Mosaic Turner Syndrome?

Yes. IVF is possible, but success rates are low. In one study on mosaic Turner syndrome and IVF, 35 IVF cycles among 22 patients resulted in:

• Implantation rate: 3.7%
• Clinical pregnancy rate: 8.6%
• Live birth (take-home baby) rate: 5.7%

Many intended mothers exploring mosaic syndrome and pregnancy consider in vitro fertilization (IVF) to achieve parenthood. The viability of IVF depends on:

• Ovarian reserve: Is there still enough follicular activity?
• Egg quality: Are the eggs chromosomally normal?
• Medical readiness: Can your body sustain pregnancy?

Some women with mosaic Turner syndrome can use their own eggs for IVF. Others may need an egg donor to achieve higher chances of success.

You may consider preimplantation genetic testing for aneuploidy (PGT-A) to reduce your chances of transferring embryos that share any chromosomal abnormalities.

How Does Turner Syndrome Affect Egg Quality and Ovarian Function?

One of the biggest factors in mosaic syndrome and pregnancy outcomes is egg health. Turner syndrome, particularly in its mosaic form, can cause early ovarian depletion, affecting both the number and quality of eggs available.

• Low AMH levels may indicate diminished ovarian reserve.
• Chromosomal abnormalities in eggs may result in failed fertilization or miscarriage.
• Hormone therapy may not always be enough to stimulate viable egg production.

If you’re considering fertility treatment, ask your doctor about ovarian reserve testing and whether IVF with your own eggs is realistic. If not, egg donation and surrogacy remain powerful options.

Learn more about how to find an egg donor.

Is It Safe to Get Pregnant if I Have Mosaic Turner Syndrome?

Even when conception is possible, pregnancy with mosaic Turner syndrome may carry serious health risks. Common complications include:

• Cardiovascular strain (e.g., aortic dissection, hypertension)
• Preeclampsia
• Increased miscarriage risk
• Stillbirth or preterm birth

Because of these risks, reproductive endocrinologists and high-risk obstetricians often recommend a full cardiovascular workup before attempting pregnancy.

If you have congenital heart or kidney conditions, pregnancy may not be medically safe and surrogacy may be the safest alternative.

What to Expect Emotionally When Navigating Fertility with Turner Syndrome

Facing infertility or repeated pregnancy loss can be emotionally exhausting. Feelings of grief, frustration and isolation are common for those managing mosaic Turner syndrome.

Coping resources that may help include:

• Support groups: The Turner Syndrome Foundation offers online support and education.
• Online communities: Communities such as r/TurnerSyndrome and What to Expect Health provide peer connection and shared experiences.
• Professional counseling: Fertility counselors can offer tools to help manage the emotional impact of infertility and clarify next steps.

When Should Someone With Mosaic Turner Syndrome Consider Surrogacy?

If you’re struggling with getting pregnant with mosaic Turner syndrome, know that you’re not alone and you’re not out of options.

You may want to consider surrogacy when:

• You’ve been advised not to carry a pregnancy for medical reasons
• IVF has failed or egg quality is too low
• You’ve experienced multiple miscarriages
• You want to avoid the medical risks of a high-risk pregnancy

With surrogacy, you can still have a biological child (with your own or a donor’s eggs), while ensuring the safest path for both baby and mother.

If you’re struggling with IVF as a result of Mosaic Turner Syndrome, learn more about what you can expect when transitioning to surrogacy after failed IVF.

How Surrogacy Circumvents the Challenges of Mosaic Turner Syndrome

For many intended mothers with mosaic Turner syndrome, the dream of having a biological child remains deeply personal even when pregnancy poses serious medical risks.

Surrogacy offers a way forward: a path to parenthood that protects your health, preserves your hope and supports your journey on your terms.

Here’s how surrogacy helps navigate the unique challenges of mosaic Turner syndrome:

• Bypasses Medical Risk: With a surrogate carrying the pregnancy, you avoid the cardiovascular, renal and miscarriage complications that often make pregnancy unsafe with Turner syndrome.
• Works With or Without Viable Eggs: Whether you’re using your own embryos or considering an egg donor, surrogacy makes biological parenthood possible even when ovarian function is limited or absent.
• Streamline by Pre-Screening: If you already have embryos from IVF, a qualified surrogate can often be matched quickly, helping you move from waiting to growing your family faster and with greater confidence.

Surrogacy doesn’t just remove the risks it opens the door to a safer, more supported version of the future you imagined.

When you’re ready to explore that path, American Surrogacy is here with expert guidance, thoroughly screened surrogates and the support you need to take the next step on your timeline.

Learn more about how our surrogates are screened to bring your dreams of parenthood within reach.

Mosaic Syndrome and Pregnancy Is Complex—But You Have Options

So, can you get pregnant with mosaic Turner syndrome? Sometimes. But even if natural conception or carrying a pregnancy isn’t possible or safe, your dream of parenthood is still within reach.

Through IVF, egg donation or surrogacy, many individuals with mosaic Turner syndrome go on to build the families they’ve always wanted.

With expert medical advice and a trusted agency like American Surrogacy by your side, you can write your own story on your own terms. Connect with us today to fast track your path to parenthood.