The shots are one of the first things people ask about when they’re considering surrogacy. It makes sense—even if you’re fine with needles at the doctor’s office, giving them to yourself at home feels different. Add in the fact that you’ll be doing this regularly for a few weeks, and it’s natural to wonder if you can handle it.
Auto-injectors could be a helpful way to manage uncertainty. These devices take a lot of the stress out of the process – and you have more options than you might think.
What Is an Auto-Injector and How Does It Work?
An auto-injector is a device that delivers medication through a needle with one button press. You position it against your skin, click, and it handles everything. From start to finish, it takes a couple of seconds.
They’re designed to minimize user error and make self-administration more straightforward. With a traditional syringe, you’re manually controlling the needle angle, insertion speed, and push rate.
By removing those variables, auto-injectors reduce the worry. It’s a bit like any assisted technology—sometimes less manual control means less mental load.
Key advantages of auto-injectors include:
- Consistent needle depth and angle every time
- Faster process (1-2 seconds)
- No need to watch the needle enter your skin
- Built-in safety features that prevent accidental needlesticks
- Reduced room for user error
Using an Auto-Injector for Surrogacy
Can you use an auto-injector during surrogacy? Often, yes—but it depends on which medication we’re talking about. Most hormonal prescriptions in the early surrogacy stages are given subcutaneously, meaning just under the skin. Auto-injectors handle these well.
Progesterone in oil—or PIO—is given as an intramuscular injection—deeper, into the muscle. PIO is oil-based and noticeably thicker than water-based medications. Why does that matter? Not every auto-injector handles it well.
That said, some auto-injectors are built specifically for intramuscular use and work with PIO. Talking to your doctor early is the important step. They’ll clarify which medications you’ll be taking, which administration methods are medically appropriate, and whether an auto-injector makes sense for your situation.
Understanding the Difference Between Subcutaneous and Intramuscular Injections
Two types of injections are used during surrogacy, and the technique and tools differ for each. Understanding which is which helps you prepare appropriately.
Subcutaneous injections go into the layer of fat just beneath your skin. You’ll give these in your abdomen or thigh area, using a shorter, thinner needle.
Most fertility hormones—Lupron, certain estrogens—fall into this category. They tend to be less uncomfortable and easier to self-administer, which makes them good candidates for auto-injectors.
Intramuscular injections go deeper, directly into muscle tissue. For surrogacy, that mainly means progesterone in oil. You’ll give these in the upper buttock or hip area with a longer needle.
Because of its oil base, the liquid is thicker and makes the shot feel more substantial. Some women have their partner help with these, though plenty manage them solo without issue.
Both techniques have their place in the surrogacy medication protocol, and knowing what to expect with each makes the process less daunting.
What’s the Best Auto-Injector for PIO?
Most standard auto-injectors weren’t designed for progesterone in oil because of the thickness and the intramuscular depth required. But specialized devices exist that handle these challenges.
Union Medico’s Super Grip is one of the more commonly mentioned options among women using surrogacy and IVF patients. It’s specifically built for intramuscular shots and accommodates PIO’s thicker consistency.
Availability varies by location, and you’ll likely need a prescription or your clinic’s approval. What works well for one person might not suit another—individual response to these tools varies more than you’d think.
If an auto-injector isn’t feasible for your PIO shots, other strategies make the process more manageable. Talk directly with your medical team about what’s available and realistic for your circumstances.
Can You Still Be a Surrogate If You Have a Fear of Needles?
Yes. A needle phobia doesn’t automatically rule you out—it just means you’ll benefit from some concrete strategies and possibly additional guidance during the medication phase.
First, this portion of the process is temporary. You’ll use injectable medications for several weeks before embryo transfer and a short period after. Once pregnancy is confirmed and progressing normally, you’ll switch to other forms or taper off certain hormones entirely. It’s not a permanent situation, even if it feels daunting at the start.
Second, familiarity reduces fear. Most women report the first one is the hardest, and each one after gets progressively easier. The more you do it, the less intimidating it becomes. Your fertility clinic will provide hands-on training, and your surrogacy agency will offer ongoing assistance throughout the process.
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Effective Ways to Reduce Injection Discomfort
Women have found these concrete methods helpful for managing discomfort and anxiety:
Before:
- Apply numbing cream like lidocaine to the site about 20–30 minutes beforehand
- Use a shot-blocker—a small plastic device that confuses your nerve receptors and dulls the needle sensation
- Apply an ice pack to numb the area, particularly for subcutaneous shots
- Try a vibrating ice pack—the vibration distracts your nerves from registering the needle prick
During:
- Take slow, measured breaths to stay relaxed
- Use distraction—music, a video, conversation with a friend or partner
After:
- Apply a heating pad to relax the muscle (especially useful after PIO)
- Use a massage ball to gently work the area and help the oil disperse, preventing lumps or tenderness
- Move around a little—light walking helps the medication distribute evenly
Making these adjustments meaningfully improves how you feel during the process. If you discover something that works part
icularly well, others will want to hear about it. The community tends to share what helps—why reinvent the wheel when someone’s already figured out the trick?
For more tips from women who’ve been through this, their experiences can provide additional strategies you might not have considered.
Getting Help During Your Medication Phase
During this phase, you don’t have to figure things out alone. Most surrogacy agencies offer resources (both practical guidance and emotional backup when you need it). If you’re feeling anxious about the shots, talk to your agency team.
They connect you with experienced women who’ve been through it. These women can share what actually worked: which products helped, which techniques made it easier.
Resources typically available through surrogacy agencies include:
- Peer connections for advice and shared experiences
- Product recommendations based on what’s helped others
- Someone to talk through your concerns with
- Help knowing what questions to ask your medical team
- Regular check-ins during this phase
Your fertility clinic will provide thorough training on safe, correct administration for each prescription. And you’re not the first to navigate this—many women before you have managed these same medications and hormones, and their experiences provide both reassurance and hands-on guidance.
Moving Forward with Confidence
Becoming a surrogate is a meaningful choice, and the shots are just one component of a much larger process. With the right tools, reliable guidance, and some adjustment time, this is quite manageable—even if needles aren’t your strong suit. Manageable, doable, and worth it.
If you have more questions about surrogacy or what the process actually looks like, feel free to reach out.